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The Department offers a major, minor and electives for undergraduates in mathematics and in computer science, and a concentration in bioinformatics. |
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Bioinformatics 101
This course provides an introduction to the features of biological data, how those data are organized and how existing data resources can be utilized efficiently by computer programs to solve a variety of biological problems. It will cover database searching and sequence analysis of DNA and protein sequences, phylogenetic analysis, visualizing and predicting protein structures, and a computer language Python to facilitate the analysis.
The prerequisite to this course is a basic understanding of molecular biology and computer programming, which are covered in BIOL 101: Biology I and CSci 120:
Introduction to Computing.
The AP biology and AP computer programming courses in high school are also sufficient. You are encouraged to speak to the instructors to gain permission.
The course will have three one-hour lectures and a 75 minute lab.
Outline of the Syllabus
- Introduction to informatics (computer technology) and its achievement (Human Genome Project)
- Introduction to DNA sequences and protein sequences (the central dogma)
- Introduction to a bioinformatics workstation (Unix, file systems, shell, web)
- NCBI Data Model and GenBank
- Sequence alignment and database searching; FASTA and BLAST
- Phylogenetic analysis
- Structure Database - PDB
- Visualizing and predicting protein structures
- Introduction to Python and Bio-Python
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Academic Catalog & Requirements
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Biologist David Hibbett (left) and computer scientist Arthur Chou (right) collaborate in the bioinformatics concentration.
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Additional Resources
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