Some information on Diseases Transmitted by the Mosquito Vector

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Mosquitoes are vectors for many important diseases. Being a vector means that it carries a disease from one host to another. Many of these diseases have a wide distribution, high mortality rate, and a high number of cases but some do not. Here you can learn some facts about a few of the mosquito vectored diseases.

 



Malaria

Dengue Fever

West Nile Virus

Japanese Encephalitis

Arboviral Encephalitis: La Crosse, St. Louis, Western Equine, and Eastern Equine Encephalitis





Malaria

Vector:

Malaria’s vector is the Anopheles  mosquito.

 Anopheles mosquito Vector of Malaria, Anopheles

Center of Disease Control & Prevention

Distribution: 

The disease is found mainly in Africa, Asia, and Latin America.  40% of the world's population is at risk of this disease. 

Distribution of Malaria

Centers for Disease Control & Prevention

                                                                                               

Number of Cases:

There are over 500,000 cases globally per year with over 1 million deaths per year.

Transmission Cycle:

The mosquito spreads the virus from person to person by the vector. 

Symptoms:

The parasite first attacks the liver and then the red blood cells.  Some symptoms are headaches, nausea, fever, and vomiting.  There can be kidney and brain complications that could result in a coma. 



                                                                        

Dengue Fever

Vector:

The vector for this disease is Aedes Aegypti .

Distribution:

It is found in Asia, Australia, Africa, South, Central, and North America. 

Dengue Fever World Distribution

Centers for Disease Control & Prevention

This distribution shows the wide distance the disease has overcome.

Number of cases:

There are about 50 to 100 million cases per year globally per year. 

Transmission cycle:

The virus is past from human to human by this mosquito. 

Symptoms:

Some symptoms are rash, fever, headache, joint pain, pain behind the eyes, muscle pain, nausea, and vomiting. In some cases the illness might progress to dengue hemorrhagic fever which causes internal bleeding and may be fatal. 

West Nile Virus ( The disease is a type of encephalitis called arboviral encephalitis)

Vector:

This virus is spread by the culex species.

Distribution:

It is found in Africa, Europe, Middle East, Central Asia, Oceania, and North America. 

Transmission Cycle:

The virus cycles from mosquito to bird. Humans and horses are incidental hosts.

West Nile Virus Life Cycle

www.fda.org

The virus uses the mosquito (the vector) to infect birds which are the main reservoirs. The horses and humans are incidentals and the vector can not get the virus back from feeding.

Number of cases:

In 2005 there were 3000 cases and 119 deaths in US. There is a 3 to 15% mortality rate. 

number of cases in US 2007

Centers for Disease Control & Prevention

This map shows the number of cases of West Nile in the year 2007.

Symptoms: 

Some symptoms are vomiting, fever, headaches, swollen lymph glands, body aches and rash.  It can sometimes lead to sever problems with the brain, spinal cord, and nerves. 


Japanese Encephalitis (this is an arboviral virus)

Vector: 

This virus is spread by the Culex Tritaeniorhynchus mosquito. 

Distribution:

It is found mostly in Asia and Australia. 

Distribution Map of Japanese Encephalitis in Asia from 1970-98

Distribution of Japanese Encephalitis in Asia

Centers for Disease Control & Prevention

This map shows how widespread the virus is in Asia. There even has been some cases in Australia.

Number of cases:

There are 35 to 50,000 cases per year with a mortality rate of 5 to 35% depending on availability of care.  

Transmission cycle:

The virus is cycled from pig host or bird host and back. Humans and horses are incidental hosts like in West Nile virus and mosquitoes can not bite a person and get the virus back. 

Symptoms:

In most cases the symptoms is a fever or headache. In serious cases it can cause paralysis, comas, seizures, and even death.



Arboviral Encephalitis

These viruses cause encephalitis and go through a transmission cycle of a primary host of a bird or small mammal.


Transmission Cycle:

The transmission cycle is about the same for the arboviral viruses. There is a main cycle between mosquitoes and birds(or sometimes small animals). The mosquitoes can bite people and horses by accident giving them the virus. The mosquitoes can not get the virus back from these hosts. They are called dead-end hosts for this reason.

The following figure shows the common cycle for La Crosse, St. Louis, Western Equine, and Eastern Equine Encephalitis.
 
Center for Disease Control & Prevention

Symptoms:

Many people do not get symptoms or they might get flu-like symptoms. Some people may get a sudden high fever and headache. In few cases some people get encephalitis which causes problems in the central nervous system including paralysis, comas, and seizures. This can cause death.


La Crosse Encephalitis


This virus's vector is Aedes triseriatus and it goes through a transmission cycle of chipmunks and squirrels to mosquitoes. Humans are incidental hosts. It is found in the upper Mid-Western States, Mid-Atlantic States, and Southeastern States. There is a mortality rate of 1% a and there are 75 cases per year in the US. 


St. Louis Encephalitis


St. Louis's vector  are the culex species found in Central and Eastern US. There have been 4651 cases from 1964 to 2005 in US. The virus has a mortality rate of 3 to 30%. The cycle and the symptoms are described above.


Western Equine Encephalitis


This virus is found in North and South America. There have been 639 cases found in US since 1964. The Culex tarsalis is the mosquito vector. Horses are greatly affected by this virus with a mortality rate of up to 50%. The cycle and symptoms are described above.


Eastern Equine Encephalitis


There have been 220 cases in US from 1964 to 2004. There are usually 5 cases per year. It is found in Georgia, Florida, Massachusetts, and New Jersey. The Culiseta melanura is the vector for this virus. The cycle and symptoms are described above.









Definitions


Vector: An organism that carries a virus from a different organism to another.

Distribution: The known location of the virus.

Mortality rate: The average percent of deaths from the total infected by the virus.

Number of cases: The amount of people infected by the virus.

Transmission Cycle: The path a virus takes from the help of a vector. Also called a life cycle of the virus.