The Larochelle Lab
at Clark University

Research Publications

Baum, P., Furlong, C., and Byers, B. (1986). Yeast gene required for spindle pole body duplication: homology of its product with Ca2+-binding proteins. Proc Natl Acad Sci U S A 83, 5512-5516.

Brinkley, B.R. (2001). Managing the centrosome numbers game: from chaos to stability in cancer cell division. Trends Cell Biol. 11, 18-21.

Daunderer, C., Schliwa, M., and Graf, R. (2001). Dictyostelium centrin-related protein (DdCrp), the most divergent member of the centrin family, possesses only two EF hands and dissociates from the centrosome during mitosis. Eur. J. Cell Biol. 80, 621-630.

Doxsey, S., Zimmerman, W., and Mikule, K. (2005). Centrosome control of the cell cycle. Trends in Cell Biology 15, 303-311.

Doxsey, S.J. (2001). Centrosomes as command centres for cellular control. Nat Cell Biol 3, E105-108.

Elbashir, S.M., Harborth, J., Weber, K., and Tuschl, T. (2002). Analysis of gene function in somatic mammalian cells using small interfering RNAs. Methods 26, 199-213.

Giehl, M., Fabarius, A., Frank, O., Hochhaus, A., Hafner, M., Hehlmann, R., and Seifarth, W. (2005). Centrosome aberrations in chronic myeloid leukemia correlate with stage of disease and chromosomal instability. Leukemia 19, 1192-1197.

Graf, R., Daunderer, C., and Schulz, I. (2004). Molecular and functional analysis of the Dictyostelium centrosome. Int. Rev. Cytol. 241, 155-202

Hinchcliffe, E.H., Miller, F.J., Cham, M., Khodjakov, A., and Sluder, G. (2001). Requirement of a centrosomal activity for cell cycle progression through G1 into S phase. Science 291, 1547-1550.

Ivanovska, I., and Rose, M.D. (2001). Fine structure analysis of the yeast centrin, Cdc31p, identifies residues specific for cell morphology and spindle pole body duplication. Genetics 157, 503-518.

Khodjakov, A., and Reider, C.L. (2001). Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression. J. Cell Biol. 153, 237-242.

Kuhlmann, M., Borisova, B.E., Kaller, M., Larsson, P., Stach, D., Na, J., Eichinger, L., Lyko, F., Ambros, V., Soderbom, F., Hammann, C., and Nellen, W. (2005). Silencing of retrotransposons in Dictyostelium by DNA methylation and RNAi. Nucleic Acids Res 33, 6405-6417.

Larochelle, D.A., Vithalani, K., and De Lozanne, A. (1996). A novel member of the rho family of small GTP-binding proteins is specifically required for cytokinesis. J. Cell Biol. 133, 1321-1330

Lingle, W.L., and Salisbury, J.L. (2000). The role of the centrosome in the development of malignant tumors. Curr. Top. Dev. Biol. 49, 313-329.

Martens, H., Novotny, J., Oberstrass, J., Steck, T.L., Postlethwait, P., and Nellen, W. (2002). RNAi in Dictyostelium: the role of RNA-directed RNA polymerases and double-stranded RNase. Mol. Biol. Cell 13, 445-453.

Muramoto, T., Suzuki, K., Shimizu, H., Kohara, Y., Kohriki, E., Obara, S., Tanaka, Y., and Urushihara, H. (2003). Construction of a gamete-enriched gene pool and RNAi-mediated functional analysis in Dictyostelium discoideum. Mech. Devel. 120, 965-975.

Paoletti, A., Moudjou, M., Paintrand, M., Salisbury, J.L., and Bornens, M. (1996). Most of centrin in animal cells is not centrosome-associated and centrosomal centrin is confined to the distal lumen of centrioles. J Cell Sci 109 ( Pt 13), 3089-3102.

Piel, M., Norberg, J., Euteneuer, U., and Bornens, M. (2001). Centrosome-dependent exit of cytokinesis in animal cells. Science 291, 1550-1553.

Pihan, G.A., Purohit, A., Wallace, J., Knecht, H., Woda, B., Quesenberry, P., and Doxsey, S.J. (1998). Centrosome defects and genetic instability in malignant tumors. Cancer Res 58, 3974-3985.

Salisbury, J.L., Suino, K.M., Busby, R., and Springett, M. (2002). Centrin-2 is required for centriole duplication in mammalian cells. Curr Biol 12, 1287-1292.

Sathasivam, K., Woodman, B., Mahal, A., Bertaux, F., Wanker, E.E., Shima, D.T., and Bates, G.P. (2001). Centrosome disorganization in fibroblast cultures derived from R6/2 Huntington's disease (HD) transgenic mice and HD patients. Hum Mol Genet 10, 2425-2435.

Saxena, K., Gaitatzes, C., Walsh, M.T., Eck, M., Neer, E.J., and Smith, T.F. (1996). Analysis of the physical properties and molecular modeling of Sec13: A WD repeat protein involved in vesicular traffic. Biochemistry 35, 15215-15221.

Schiebel, E., and Bornens, M. (1995). In search of a function for centrins. Trends Cell Biol 5, 197-201.

Schwarz, D.S., Hutvagner, G., Du, T., Xu, Z., Aronin, N., and Zamore, P.D. (2003). Asymmetry in the assembly of the RNAi enzyme complex. Cell 115, 199-208.

Silva, J.M., Mizuno, H., Brady, A., Lucito, R., and Hannon, G.J. (2004). RNA interference microarrays: high-throughput loss-of-function genetics in mammalian cells. Proc Natl Acad Sci U S A 101, 6548-6552

Zamora, I., and Marshall, W.F. (2005). A mutation in the centriole-associated protein centrin causes genomic instability via increased chromosome loss in Chlamydomonas reinhardtii. BMC Biol 3, 15.

Zhao, J., Ren, Y., Jiang, Q., and Feng, J. (2003). Parkin is recruited to the centrosome in response to inhibition of proteasomes. J Cell Sci 116, 4011-4019.

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